The law of duty demands moral perfection or holiness. But this is impossible in our present life, therefore it can only be attained by an indefinite progress, and this progress is only possible under the hypothesis of an existence and a personality that re indefinitely prolonged.

Creation is not an instantaneous act, but is an eternal process. The immanence of God which follows from this hypothesis is the pledge that evil and error, ugliness and imperfection are not ultimate. Evil has reference to the distance which good has to traverse. Error is the stage on the pathway to truth.

Belief in the intrinsic unity of knowledge – the reality of the labyrinth – rides ultimately on the hypothesis that every mental process has a physical grounding and is consistent with the natural sciences.

I cannot give any scientist of any age better advice than this: the intensity of conviction that a hypothesis is true has no bearing over whether it is true or not.

Properly, there is no other knowledge but that which is got by working; the rest is yet all a hypothesis of knowledge; a thing to be argued of in schools; a thing floating in the clouds. endless logic vortices, till we try and fix it.

Every science begins as philosophy and ends as art; it arises in hypothesis and flows into achievement.

The world would be consistent without God; it would also be consistent with God; whichever hypothesis a man adopts will fit experience equally well.

A fact is a simple statement that everyone believes. It is innocent, unless found guilty. A hypothesis is a novel suggestion that no one wants to believe. It is guilty, until found effective.

One must credit an hypothesis with all that has had to be discovered in order to demolish it.

The man of science who cannot formulate a hypothesis is only an accountant of phenomena.

To find the point where hypothesis and fact meet; the delicate equilibrium between dream and reality; the place where fantasy and earthly things are metamorphosed into a work of art; the hour when faith in the future becomes knowledge of the past; to lay down one's power for others in need; to shake off the old ordeal and get ready for the new; to question, knowing that never can the full answer be found; to accept uncertainties quietly, even our incomplete knowledge of God; this is what man's journey is about, I think.

If far-reaching discoveries regarding the nature of matter and energy and the laws which govern the Universe have been made and worked on by civilizations that have disappeared, and if some of them have been preserved throughout the ages (which is by no means certain) this could only have been done by people of superior intelligence and in a language necessarily incomprehensible to the ordinary man. If, however, we reject this hypothesis we can nevertheless imagine, from one age to another, a succession of beings of exceptional gifts able to communicate with one another. Such beings are well aware that it is not in their interests to display their powers openly.

The quantum hypothesis will eventually find its exact expression in certain equations which will be a more exact formulation of the law of causality.

It's my hypothesis that the individual is not a pre-given entity which is seized on by the exercise of power. The individual, with his identity and characteristics, is the product of a relation of power exercised over bodies, multiplicities, movements, desires, forces.

In both social and natural sciences, the body of positive knowledge grows by the failure of a tentative hypothesis to predict phenomena the hypothesis professes to explain; by the patching up of that hypothesis until someone suggests a new hypothesis that more elegantly or simply embodies the troublesome phenomena, and so on ad infinitum. In both, experiment is sometimes possible, sometimes not (witness meteorology). In both, no experiment is ever completely controlled, and experience often offers evidence that is the equivalent of controlled experiment. In both, there is no way to have a self-contained closed system or to avoid interaction between the observer and the observed. The Gödel theorem in mathematics, the Heisenberg uncertainty principle in physics, the self-fulfilling or self-defeating prophecy in the social sciences all exemplify these limitations.

Creationists sometimes claim that scientists have a vested interest in the concept of biological evolution and are unwilling to consider other possibilities. But this claim, too, misrepresents science. Scientists continually test their ideas against observations and submit their work to their colleagues for critical peer review of ideas, evidence, and conclusions before a scientific paper is published in any respected scientific journal. Unexplained observations are eagerly pursued because they can be signs of important new science or problems with an existing hypothesis or theory. History is replete with scientists challenging accepted theory by offering new evidence and more comprehensive explanations to account for natural phenomena. Also, science has a competitive element as well as a cooperative one. If one scientist clings to particular ideas despite evidence to the contrary, another scientist will attempt to replicate relevant experiments and will not hesitate to publish conflicting evidence. If there were serious problems in evolutionary science, many scientists would be eager to win fame by being the first to provide a better testable alternative. That there are no viable alternatives to evolution in the scientific literature is not because of vested interests or censorship but because evolution has been and continues to be solidly supported by evidence.

There Is No God. This negation must be understood solely to affect a creative Deity. The hypothesis of a pervading Spirit co-eternal with the universe remains unshaken.

It is a common failing–and one that I have myself suffered from–to fall in love with a hypothesis and to be unwilling to take no for an answer. A love affair with a pet hypothesis can waste years of precious time. There is very often no finally decisive yes, though quite often there can be a decisive no.

There is nothing distinctively scientific about the hypothetico-deductive process. It is not even distinctively intellectual. It is merely a scientific context for a much more general stratagem that underlies almost all regulative processes or processes of continuous control, namely feedback, the control of performance by the consequences of the act performed. In the hypothetico-deductive scheme the inferences we draw from a hypothesis are, in a sense, its logical output. If they are true, the hypothesis need not be altered, but correction is obligatory if they are false. The continuous feedback from inference to hypothesis is implicit in Whewell's account of scientific method; he would not have dissented from the view that scientific behaviour can be classified as appropriately under cybernetics as under logic.

Before entering upon the subject-matter of these new memoirs, I must explain an hypothesis which will undoubtedly seem strange, but in the absence of which it is impossible for me to proceed intelligibly: I mean the hypothesis of a God.